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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1988-10-7
|
| pubmed:abstractText |
Previously we have identified a mouse genomic clone (clone 5) which specifies the 5' flanking region and the 5' terminal exon of an interferon-activatable gene (202 gene). Here, we show that about 5 kb upstream from this flanking region in clone 5 there occurs a 3' terminal region of a second interferon-activatable gene (203 gene). The two genes are transcribed in the same direction. Segments from the 203 gene can be hybridized to a set of five interferon-inducible RNAs. The 203 mRNAs are induced about 15-fold in interferon-treated Ehrlich ascites tumor cells.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0042-6822
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
166
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
24-9
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:2457983-Animals,
pubmed-meshheading:2457983-Chromosome Mapping,
pubmed-meshheading:2457983-Cloning, Molecular,
pubmed-meshheading:2457983-Gene Expression Regulation,
pubmed-meshheading:2457983-Genes,
pubmed-meshheading:2457983-Genetic Linkage,
pubmed-meshheading:2457983-Interferons,
pubmed-meshheading:2457983-Mice,
pubmed-meshheading:2457983-RNA, Messenger,
pubmed-meshheading:2457983-Time Factors,
pubmed-meshheading:2457983-Transcription, Genetic,
pubmed-meshheading:2457983-Tumor Cells, Cultured
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Interferons as gene activators: close linkage of two interferon-activatable murine genes.
|
| pubmed:affiliation |
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|