Linked Life Data

2456224

Source:http://linkedlifedata.com/resource/pubmed/id/2456224

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-8-26
pubmed:abstractText
To examine the significance of a disturbed lymph drainage for the pathogenesis of acute necrotizing pancreatitis, thoracic duct ligation was performed in 53 Wistar rats. Histological examination of the pancreas and analysis of serum lipase and serum amylase were carried out at various time intervals from 1 h to 42 days after initiating the experiment. Sudden stop of the lymph flow induced a long lasting pancreatic edema, initially in the perilobular interstitium and eventually also within some lobules, with scattered necroses of whole acini or single acinar cells mainly in the peripheral zones of the lobuli. In addition, a marked interstitial inflammatory infiltrate developed, resembling lipophage granulomas. This was most likely due to alymphangeal reflux of sunflower oil, applicated for the visualization of the thoracic duct. These findings suggest that changes in the lymph flow may favour the development of acute necrotizing pancreatitis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0232-1513
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
95-101
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Significance of disturbed lymph flow for the pathogenesis of pancreatitis. I. Ligature of the ductus thoracicus in the rat.
pubmed:affiliation
Institute of Pathological Anatomy, University of Rostock.
pubmed:publicationType
Journal Article