Linked Life Data

2455629

Source:http://linkedlifedata.com/resource/pubmed/id/2455629

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-8-12
pubmed:abstractText
The cerebral event-related potentials (ERPs) and reaction times (RTs) of 8 drug-free depressed in-patients (mean age 58, with marked psychomotor retardation) were recorded during a dichotic listening and choice RT task and compared to those of 9 healthy, age-matched controls. The depressed showed significantly longer, more variable RTs than the controls and made more mistakes. Their ERPs for targets in the attended ear differed significantly from those of the controls by the small amplitude (or absence) of the N2 vertex component elicited by the controls in such a situation and by the presence in the same situation of a late frontal slow negativity (LFN) that did not show up in the grand average ERP of the control group. These results were discussed in terms of the two components of the processing negativity described by Näätänen (1982, 1985) and according to resource models of attention: whereas the controls would perform this easy task quickly thanks to quasi-automatic matching processes (reflected by the vertex N2), the depressed would need further effortful, controlled processing (reflected by the LFN) to perform the task.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0013-4694
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
46-55
pubmed:dateRevised
2008-9-9
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Attention impairment and psychomotor retardation in depressed patients: an event-related potential study.
pubmed:affiliation
LENA-CNRS UA-654, Hôpital de la Salpêtrière, Paris, France.
pubmed:publicationType
Journal Article