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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-8-8
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pubmed:abstractText |
A familial link between schizophrenia and antisocial behavior has been established (e.g., Silverton, 1985). This study examined this relationship in a Danish cohort. The subjects were 36 high-risk males (offspring of a schizophrenic parent) and 36 low-risk males (offspring of parents without psychopathology). This high-risk subjects exhibited more antisocial behavior than the low-risk subjects. We tested the hypothesis of a correlation between neurointegrative deficits, as defined by motor impairment, and antisocial behavior, rated at ages 10-13, in subjects at genetic risk for schizophrenia. Path analyses were conducted from motor impairment at 1 year and motor impairment at 10-13 years to antisocial behavior separately for high-risk and low-risk subjects. Adolescent motor impairment was a significant predictor of antisocial behavior for high-risk subjects. Motor impairment at 1 year was also associated with antisocial behavior for these subjects, although the association was partly due to the indirect effects of motor impairment at 1 year on motor impairment at 10-13 years, which, in turn, was associated with changes in antisocial behavior. As predicted, none of the path coefficients nor the effect coefficient was significant for low-risk subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0091-0627
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-86
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2454981-Adolescent,
pubmed-meshheading:2454981-Antisocial Personality Disorder,
pubmed-meshheading:2454981-Child,
pubmed-meshheading:2454981-Developmental Disabilities,
pubmed-meshheading:2454981-Humans,
pubmed-meshheading:2454981-Infant,
pubmed-meshheading:2454981-Male,
pubmed-meshheading:2454981-Motor Skills,
pubmed-meshheading:2454981-Risk Factors,
pubmed-meshheading:2454981-Schizophrenia
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pubmed:year |
1988
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pubmed:articleTitle |
Motor impairment and antisocial behavior in adolescent males at high risk for schizophrenia.
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pubmed:affiliation |
Department of Psychology, University of Nevada, Reno 89557.
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pubmed:publicationType |
Journal Article
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