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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-6-23
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pubmed:abstractText |
Effusion recurrence is a major problem in the palliative care of patients with disseminated cancer. Thirty-two patients with recurrent malignant pleural effusions were treated with intracavitary natural beta-interferon at increasing doses (5-20 million units) for a maximum of three administrations. Among 29 evaluable patients, 11 showed complete (27.6%) or partial (10.3%) remission. No difference in response rate was observed according to sex, age, and histological type. All the responses were observed in patients with an effusion volume less than 1,000 ml (11/16; 68.8%). No side effect was observed. In conclusion, intrapleural beta-interferon is promising as a palliative in the treatment of recurrent malignant effusions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
253-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2453008-Adenocarcinoma,
pubmed-meshheading:2453008-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:2453008-Carcinoma, Small Cell,
pubmed-meshheading:2453008-Drug Evaluation,
pubmed-meshheading:2453008-Female,
pubmed-meshheading:2453008-Humans,
pubmed-meshheading:2453008-Injections,
pubmed-meshheading:2453008-Interferon Type I,
pubmed-meshheading:2453008-Lung Neoplasms,
pubmed-meshheading:2453008-Male,
pubmed-meshheading:2453008-Mesothelioma,
pubmed-meshheading:2453008-Palliative Care,
pubmed-meshheading:2453008-Pleura,
pubmed-meshheading:2453008-Pleural Effusion,
pubmed-meshheading:2453008-Recurrence
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pubmed:year |
1988
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pubmed:articleTitle |
Intrapleural natural beta interferon in the treatment of malignant pleural effusions.
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pubmed:affiliation |
Dipartimenti di Oncologia Medical e Anatomia Patologica, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italia.
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pubmed:publicationType |
Journal Article
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