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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-6-20
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pubmed:abstractText |
Preoperative serum CA 125 levels were determined for 36 patients with Stage I and II ovarian carcinoma. Levels ranged from 9 to 1962 U/ml with a mean of 216 U/ml. In Stage I patients, CA 125 levels averaged 133 U/ml and in Stage II patients 382 U/ml. Nine of 24 Stage I (38%) and 9 of 12 Stage II patients (75%) had CA 125 levels in excess of 65 U/ml in a population somewhat overrepresented in mucinous tumors. Patients with non-mucinous neoplasms had CA 125 elevations more often--in 75% of the cases--than those with mucinous tumors. A larger study will be required to more precisely estimate the fraction of early stage patients with elevated preoperative serum CA 125 levels; however, this investigation demonstrates an assay sensitivity minimally adequate to initiate a pilot evaluation of serum CA 125 levels in a population at risk for ovarian carcinoma.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0090-8258
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7-14
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2452773-Antigens, Neoplasm,
pubmed-meshheading:2452773-Antigens, Surface,
pubmed-meshheading:2452773-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:2452773-Epitopes,
pubmed-meshheading:2452773-Female,
pubmed-meshheading:2452773-Humans,
pubmed-meshheading:2452773-Middle Aged,
pubmed-meshheading:2452773-Neoplasm Staging,
pubmed-meshheading:2452773-Ovarian Neoplasms
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pubmed:year |
1988
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pubmed:articleTitle |
An initial analysis of preoperative serum CA 125 levels in patients with early stage ovarian carcinoma.
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pubmed:affiliation |
Gynecologic Oncology Laboratories, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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