Linked Life Data

2451890

Source:http://linkedlifedata.com/resource/pubmed/id/2451890

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-5-13
pubmed:abstractText
The incidence of malignant disease in AIDS patients is around 40%. Ninety percent of the tumors are Kaposi's sarcoma and 10% are malignant lymphomas, predominantly of B cell origin. The natural history of the AIDS-associated Kaposi's sarcoma is variable. It may remain entirely asymptomatic without treatment for many months or it may be rapidly progressive and produce life-threatening pulmonary, cardiac, or gastrointestinal symptoms requiring acute therapeutic intervention. The malignant lymphomas occurring in AIDS patients are usually very aggressive in their natural history. The treatment of choice for symptomatic Kaposi's sarcoma and malignant lymphoma is chemotherapy. In general, such treatment can alleviate symptoms and improve the quality of life in AIDS patients; however, the underlying immune defect is not improved by such treatment and the patients remain susceptible to life-threatening opportunistic infections. The ultimate control of the malignancies associated with AIDS depends upon the development of therapies capable of reversing the underlying immune defect.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0003-4738
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
310-23
pubmed:dateRevised
2006-4-24
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Clinical, biologic, and therapeutic aspects of malignancies associated with the acquired immunodeficiency syndrome: Part I and Part II.
pubmed:affiliation
Division of Cancer Treatment, National Cancer Institute, Frederick Cancer Research Facility, Maryland 21701.
pubmed:publicationType
Journal Article