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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1988-5-10
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pubmed:abstractText |
An unpreserved artificial tear substitute containing 0.1% sodium hyaluronate was compared with a preparation containing 1.4% polyvinyl alcohol and 0.5% chlorobutanol in a controlled, double-masked, randomized study in patients with moderately severe keratoconjunctivitis sicca. Patients were evaluated initially, at 1, 4, and 8 weeks. The dry-eye status was evaluated by means of tear-film osmolality, tear breakup time, rose bengal staining, Schirmer's test (without anesthesia), and ocular surface-impression cytology. In general, neither preparation was found to be superior to the other. In both study groups, the mean tear-film osmolality and rose bengal staining score improved over the eight-week study, but the degree of squamous metaplasia of the bulbar conjunctival surface, as shown by impression cytology, did not change significantly.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Hyaluronic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Polyvinyl Alcohol,
http://linkedlifedata.com/resource/pubmed/chemical/Povidone,
http://linkedlifedata.com/resource/pubmed/chemical/Povidone-Iodine,
http://linkedlifedata.com/resource/pubmed/chemical/Rose Bengal
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-9950
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
106
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
484-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2451494-Clinical Trials as Topic,
pubmed-meshheading:2451494-Humans,
pubmed-meshheading:2451494-Hyaluronic Acid,
pubmed-meshheading:2451494-Keratoconjunctivitis,
pubmed-meshheading:2451494-Keratoconjunctivitis Sicca,
pubmed-meshheading:2451494-Osmolar Concentration,
pubmed-meshheading:2451494-Palliative Care,
pubmed-meshheading:2451494-Polyvinyl Alcohol,
pubmed-meshheading:2451494-Povidone,
pubmed-meshheading:2451494-Povidone-Iodine,
pubmed-meshheading:2451494-Rose Bengal,
pubmed-meshheading:2451494-Staining and Labeling
|
pubmed:year |
1988
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pubmed:articleTitle |
Sodium hyaluronate and polyvinyl alcohol artificial tear preparations. A comparison in patients with keratoconjunctivitis sicca.
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pubmed:affiliation |
Department of Ophthalmology, St Paul-Ramsey Medical Center, MN 55101.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|