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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
1988-3-25
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pubmed:abstractText |
The action of emetine on the incorporation of (14C)1-DL-valine and (14C)-8-adenine in TCA insoluble fraction of axenic Entamoeba histolytica was investigated. These compounds were almost exclusively incorporated in the 'protein' and 'RNA' fractions, respectively. Incorporation of the purine showed a significantly higher sensitivity to emetine. While the percentage inhibition of valine incorporation by emetine decreased with increasing pH, the susceptibility of adenine incorporation was greater in the alkaline range.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0176-6724
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
266
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
575-9
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pubmed:dateRevised |
2009-6-8
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pubmed:meshHeading |
pubmed-meshheading:2449783-Adenine,
pubmed-meshheading:2449783-Animals,
pubmed-meshheading:2449783-Culture Media,
pubmed-meshheading:2449783-Emetine,
pubmed-meshheading:2449783-Entamoeba histolytica,
pubmed-meshheading:2449783-Hydrogen-Ion Concentration,
pubmed-meshheading:2449783-Kinetics,
pubmed-meshheading:2449783-Protein Biosynthesis,
pubmed-meshheading:2449783-RNA,
pubmed-meshheading:2449783-Trichloroacetic Acid,
pubmed-meshheading:2449783-Valine
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pubmed:year |
1987
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pubmed:articleTitle |
Sensitivity of protein and RNA synthesis to emetine in axenic Entamoeba histolytica.
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pubmed:affiliation |
Department of Biochemistry, Central Drug Research Institute, Lucknow, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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