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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1988-3-18
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pubmed:abstractText |
In 16 patients affected with acute leukemia (7 patients with acute lymphatic leukemia and 9 patients with acute myeloid leukemia) the resonance thrombogramme was recorded during cytostatic induction therapy, coagulation factor XIII (subunit XIII-A, XIII-S) and further hemostasiological parameters were determined. Subunit XIII-A was lowered to 36%, subunit XIII-S to 65% and the fibrin formation time of the resonance thrombogramme was extended to 9 minutes. There exists a negative correlation between component XIII-A and fibrin formation time r = -0.48 (p less than 0.01). The influence exerted by diminishing factor XIII and fibrin(ogen) splitting products on the fibrin formation time was investigated in in-vitro tests. A diminution of factor XIII below 10% will extend the fibrin formation time to about 10 minutes, an increase of fibrin(ogen) splitting products to 100 micrograms/ml to about 3 minutes.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0323-4347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
670-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2448208-Adult,
pubmed-meshheading:2448208-Aged,
pubmed-meshheading:2448208-Blood Coagulation Tests,
pubmed-meshheading:2448208-Factor XIII,
pubmed-meshheading:2448208-Factor XIII Deficiency,
pubmed-meshheading:2448208-Fibrin,
pubmed-meshheading:2448208-Fibrin Fibrinogen Degradation Products,
pubmed-meshheading:2448208-Humans,
pubmed-meshheading:2448208-Leukemia, Lymphoid,
pubmed-meshheading:2448208-Leukemia, Myeloid, Acute,
pubmed-meshheading:2448208-Middle Aged
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pubmed:year |
1987
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pubmed:articleTitle |
[Detection of factor XIII deficiency in acute leukemia with resonance thrombography].
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pubmed:affiliation |
Klinik für Innere Medizin, Bereiches Medizin, Wilhelm-Pieck-Universität Rostock.
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pubmed:publicationType |
Journal Article,
English Abstract
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