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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1988-2-10
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pubmed:abstractText |
1. Compared with the peripheral blood lymphocytes of healthy children the cell fractions in the S- and G2 + M-phase are significantly higher in the bone-marrow of those children affected with ALL. This increase was proved in the SR- and MR-group irrespective of the cytomorphological subtype and cytochemical reaction. In patients with relapses the percentage of S-phase cells is below 6%. 2. In about 30% of our patients (mainly in the SR-group with L1-morphology) an initial DNA-aneuploidy was identified. As the risk of relapse is higher in children without DNA-aneuploidy, this symptom has a pretherapeutical-prognostic significance. 3. In the phase of hematological full remission, DNA-frequency distribution correlates with the proliferative activity of normal hematopoiesis. It provides no additional information about the pretherapeutical risk.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:issn |
0323-4347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
530-41
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2446994-Adolescent,
pubmed-meshheading:2446994-Aneuploidy,
pubmed-meshheading:2446994-Bone Marrow,
pubmed-meshheading:2446994-Cell Division,
pubmed-meshheading:2446994-Child,
pubmed-meshheading:2446994-Child, Preschool,
pubmed-meshheading:2446994-Cytophotometry,
pubmed-meshheading:2446994-Female,
pubmed-meshheading:2446994-Humans,
pubmed-meshheading:2446994-Infant,
pubmed-meshheading:2446994-Leukemia, Lymphoid,
pubmed-meshheading:2446994-Lymphocytes,
pubmed-meshheading:2446994-Male,
pubmed-meshheading:2446994-Prognosis
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pubmed:year |
1987
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pubmed:articleTitle |
[Impulse cytophotometric studies of bone marrow and blood cells in children with acute lymphoblastic leukemia (ALL). 1. Bone marrow cells].
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pubmed:affiliation |
Klinik und Poliklinik für Kinderheilkunde, Martin-Luther-Universität Halle-Wittenberg.
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pubmed:publicationType |
Journal Article,
English Abstract
|