Linked Life Data

2446836

Source:http://linkedlifedata.com/resource/pubmed/id/2446836

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-2-18
pubmed:abstractText
This experiment investigated the effects of 3 concentrations (15%, 25% and 35%) of nitrous oxide (N2O) on reaction time (RT) and P300 latency and amplitude. Ten subjects responded to visually presented male or female names in an oddball paradigm with accuracy controlled at a high level. The results were analysed on a single-trial basis. Nitrous oxide increased both RT and P300 latency in a dose-related manner and these variables showed a strong between-dose correlation (r = 0.67). Nitrous oxide also decreased P300 amplitude but only up to the 25% dose. The between-dose correlation for P300 amplitude and RT was negligible (r = -0.14). These results suggest that P300 latency is an index of N2O narcosis and are interpreted as indicating that narcosis involves the slowing of stimulus evaluation processes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0013-4694
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
171-8
pubmed:dateRevised
2008-9-9
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
The effects of nitrous oxide on P300 and reaction time.
pubmed:affiliation
Department of Physical Education, York University, Ont, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't