Linked Life Data

2445675

Source:http://linkedlifedata.com/resource/pubmed/id/2445675

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
84
pubmed:dateCreated
1988-1-12
pubmed:abstractText
Further studies on macrophage synthesis of nitrite and nitrate showed lipopolysaccharide (LPS) and interferon (IFN) to be potent stimuli. Kinetic experiments showed a time lag of 6 h for LPS and 10-12 h for IFN. The protein synthesis inhibitor cycloheximide completely inhibited nitrite and nitrate synthesis when present in the media at time 0 but had no effect if added at times after the lag period. A number of experiments were carried out to test the involvement of reactive oxygen species (the 'oxygen burst') in stimulated macrophage synthesis. All results were consistent with a lack of involvement of the oxygen burst in this process.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5038
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
335-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Further studies on murine macrophage synthesis of nitrite and nitrate.
pubmed:affiliation
Department of Applied Biological Sciences, Massachusetts Institute of Technology, Cambridge 02139.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.