rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
1987-11-27
|
pubmed:abstractText |
Endodeoxyribonuclease was detected in rat neocortex chromatin. The partly purified enzyme was found to influence the superhelical apurine-apyrimidine DNA 50 times as effectively as compared to the native substrate. The enzyme hydrolyzes the phosphodiester bond with the formation of 3'-OH- and 5'-phosphate terminal groups. The enzyme-hydrolyzed DNA is an effective primer for DNA-polymerase I from E. coli. It was assumed that DNAase from rat brain chromatin is an apurine-apyrimidine endonuclease II.
|
pubmed:language |
rus
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0320-9725
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
52
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1133-7
|
pubmed:dateRevised |
2007-7-23
|
pubmed:meshHeading |
pubmed-meshheading:2444272-Animals,
pubmed-meshheading:2444272-Brain,
pubmed-meshheading:2444272-DNA, Superhelical,
pubmed-meshheading:2444272-DNA Polymerase I,
pubmed-meshheading:2444272-DNA Repair,
pubmed-meshheading:2444272-DNA-(Apurinic or Apyrimidinic Site) Lyase,
pubmed-meshheading:2444272-Deoxyribonuclease IV (Phage T4-Induced),
pubmed-meshheading:2444272-Endodeoxyribonucleases,
pubmed-meshheading:2444272-Hydrolysis,
pubmed-meshheading:2444272-Rats,
pubmed-meshheading:2444272-Rats, Inbred Strains
|
pubmed:year |
1987
|
pubmed:articleTitle |
[Specific for apurine-apyrimidine DNA endodeoxyribonuclease from the rat brain].
|
pubmed:publicationType |
Journal Article,
English Abstract
|