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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1987-10-27
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pubmed:abstractText |
A patient who suffered a severe hypotensive episode after induction of anaesthesia, was subsequently found to show positive skin-test responses to suxamethonium. Investigation revealed that suxamethonium induced basophils from the patient to release histamine to an extent comparable to that found after exposure to anit-IgE. Basophils from control subjects showed no such response. Basophil histamine release may offer a useful approach to the investigation of adverse drug reactions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0003-2409
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
850-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2444131-Adult,
pubmed-meshheading:2444131-Antibodies, Anti-Idiotypic,
pubmed-meshheading:2444131-Basophils,
pubmed-meshheading:2444131-Drug Hypersensitivity,
pubmed-meshheading:2444131-Female,
pubmed-meshheading:2444131-Histamine Release,
pubmed-meshheading:2444131-Humans,
pubmed-meshheading:2444131-Hypersensitivity, Immediate,
pubmed-meshheading:2444131-Immunoglobulin E,
pubmed-meshheading:2444131-Succinylcholine
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pubmed:year |
1987
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pubmed:articleTitle |
Basophil histamine release. A study in allergy to suxamethonium.
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pubmed:affiliation |
Department of Anaesthesia, St Thomas' Hospital, London.
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pubmed:publicationType |
Journal Article,
Case Reports
|