Linked Life Data

2442010

Source:http://linkedlifedata.com/resource/pubmed/id/2442010

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-10-19
pubmed:abstractText
Spontaneous electrical and mechanical activity was observed when single myocytes from guinea-pig hearts were loaded with sodium by direct intracellular application. Transient membrane depolarizations were found to be due to spontaneous inward currents (Isp). Both Isp and spontaneous contractions were abolished by 2',3'-benzobenzamil or 3',4'-dichlorobenzamil, two compounds that were previously reported to inhibit Na+/Ca2+ exchange. These findings suggest that the spontaneous membrane currents in Na+-loaded myocytes could be generated by the Na+/Ca2+ exchange mechanism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
4
pubmed:volume
140
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Amiloride derivatives that block Na+/Ca2+ exchange inhibit spontaneous inward currents in Na+-loaded cardiac myocytes.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't