Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1987-9-1
pubmed:abstractText
The purified ermC methyltransferase described here incorporates two methyl groups per Bacillus subtilis 23S rRNA molecule in vitro. The Km for S-adenosyl-L-methionine was 12 microM, and for B. subtilis 23S rRNA the Km was 375 nM. In vivo methylation specified by several related resistance determinants prevented in vitro methylation by the ermC enzyme, suggesting that methylation specified by all of these determinants occurs at homologous sites. Since methyl groups were incorporated in protein-free 23S rRNA molecules, the structure of rRNA alone must contain sufficient information to specify the methylation site.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-104975, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-109873, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-202081, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-3087948, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-3096970, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-3906713, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-4683489, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-4731016, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-4868544, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-499508, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-5279527, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6163765, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6195156, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6203682, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6206780, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6276096, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6298066, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6374617, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6429477, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6770759, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6780509, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-6792593, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-7005624, http://linkedlifedata.com/resource/pubmed/commentcorrection/2440853-96738
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0021-9193
pubmed:author
pubmed:issnType
Print
pubmed:volume
169
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3857-60
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Site and substrate specificity of the ermC 23S rRNA methyltransferase.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.