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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1987-9-3
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pubmed:abstractText |
The ability of nonadherent peripheral blood mononuclear cells of normal individuals to lyse noninfected and cytomegalovirus (CMV)-infected human fibroblasts was enhanced by preincubation with recombinant human alpha interferon (alpha-rIFN) or beta (beta-rIFN). In contrast, recombinant human gamma IFN (gamma-rIFN) augmented natural killing (NK) against both targets relatively poorly. Recombinant or natural human interleukin 2(IL-2) also augmented NK against noninfected and CMV-infected targets. Augmentation of NK by IFN or IL-2 could be blocked by the addition of corresponding antisera. IL-2-enhanced NK against CMV-infected targets was usually independent of alpha-IFN production.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-114591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-223110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-2579152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-286738,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-3081640,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-308989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-309487,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-3098472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-310861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-3918102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-4320336,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-524066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6095498,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6154652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6160103,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6160906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6164729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6175462,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6203975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6203980,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6236888,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6260861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6281647,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6308051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6309674,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6320509,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6329567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6403469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6409427,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6411624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6434688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6440995,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-650156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6607776,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6610516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-6982930,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2440628-7000676
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0009-9104
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
372-82
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2440628-Cytomegalovirus Infections,
pubmed-meshheading:2440628-Cytotoxicity, Immunologic,
pubmed-meshheading:2440628-Fibroblasts,
pubmed-meshheading:2440628-Humans,
pubmed-meshheading:2440628-Interferon Type I,
pubmed-meshheading:2440628-Interferon-gamma,
pubmed-meshheading:2440628-Interferons,
pubmed-meshheading:2440628-Interleukin-2,
pubmed-meshheading:2440628-Killer Cells, Natural,
pubmed-meshheading:2440628-Kinetics,
pubmed-meshheading:2440628-Recombinant Proteins
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pubmed:year |
1987
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pubmed:articleTitle |
Effects of interferons and interleukin 2 on natural killing of cytomegalovirus-infected fibroblasts.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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