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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1987-8-19
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pubmed:abstractText |
A phase II study of peplomycin, an analogue of bleomycin, was carried out in 42 patients with advanced or recurrent breast cancer by a cooperative group consisting of 15 institutes throughout Japan, and the following results were obtained. Among the 42 patients, 38 were evaluable, in whom the overall response rate was 7.9% (3/38). For the various histologic types, the response rate was 33.3% (2/6) for papillotubular carcinoma and 9.1% (1/11) for medullary tubular carcinoma. The response rate was 33.3% (2/6) in patients without prior treatment and 3.1% (1/32) in those with prior treatment. Side effects of nausea, anorexia, malaise, alopecia and pyrexia occurred frequently, and a decrease in WBC and an increase in GOT were observed temporally. Pulmonary toxicity was observed in 7 patients.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
2347-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2440387-Adult,
pubmed-meshheading:2440387-Aged,
pubmed-meshheading:2440387-Anorexia,
pubmed-meshheading:2440387-Bleomycin,
pubmed-meshheading:2440387-Breast Neoplasms,
pubmed-meshheading:2440387-Carcinoma,
pubmed-meshheading:2440387-Carcinoma, Papillary,
pubmed-meshheading:2440387-Drug Evaluation,
pubmed-meshheading:2440387-Female,
pubmed-meshheading:2440387-Humans,
pubmed-meshheading:2440387-Middle Aged,
pubmed-meshheading:2440387-Nausea,
pubmed-meshheading:2440387-Neoplasm Recurrence, Local,
pubmed-meshheading:2440387-Peplomycin
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pubmed:year |
1987
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pubmed:articleTitle |
[Phase II study of peplomycin in breast cancer. A cooperative study. Clinical Study Group of Peplomycin for Breast Cancer in Japan].
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pubmed:publicationType |
Journal Article,
English Abstract
|