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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1987-8-24
|
| pubmed:abstractText |
Sixty renal allograft tissues obtained from 29 patients were stained with hematoxylin and eosin. These tissues were histologically classified into 4 patterns according to the distribution pattern of the infiltrating cells: normal, focal, focal-diffuse, and diffuse types. Clinical signs of acute rejection were observed in 88% of the patients with the diffuse type infiltration, and 83% of those with the focal-diffuse type infiltration but in only 13% of those with the focal type infiltration. Twenty-four renal allografts were analyzed by the ABC and the IGSS methods using monoclonal antibodies. The number of T cells (Leu 1) accounted for about 80% of the total number of infiltrating cells; 2-8% of the cells were B cells (Leu 12); about 10% were NK/K cells (Leu 7); and 4-6% were monocytes/macrophages (Leu M3). As to helper/inducer T cell (Leu3a) and killer/suppressor T cell (Leu2a), which are T lymphocyte subsets, there were more Leu3a- than Leu2a-positive cells in focal type tissue, but there were more Leu2a- than Leu3a-positive cells in focal-diffuse and diffuse type tissue. In most cases that developed clinical signs of acute rejection, there were more Leu2a- than Leu3a-positive cells. The Leu3a/Leu2a ratio in most of the AZA-administered cases dropped immediately after the transplantation and maintained a low value, but in the CSA-administered cases it decreased gradually post-transplant.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0041-1337
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
44
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
43-50
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2440161-Adolescent,
pubmed-meshheading:2440161-Adult,
pubmed-meshheading:2440161-Antibodies, Monoclonal,
pubmed-meshheading:2440161-Antigens, Surface,
pubmed-meshheading:2440161-Child,
pubmed-meshheading:2440161-Female,
pubmed-meshheading:2440161-Gold,
pubmed-meshheading:2440161-Graft Rejection,
pubmed-meshheading:2440161-Humans,
pubmed-meshheading:2440161-Immunoenzyme Techniques,
pubmed-meshheading:2440161-Inflammation,
pubmed-meshheading:2440161-Kidney,
pubmed-meshheading:2440161-Kidney Transplantation,
pubmed-meshheading:2440161-Lymphocytes,
pubmed-meshheading:2440161-Macrophages,
pubmed-meshheading:2440161-Male,
pubmed-meshheading:2440161-Middle Aged,
pubmed-meshheading:2440161-Monocytes,
pubmed-meshheading:2440161-Staining and Labeling,
pubmed-meshheading:2440161-Transplantation, Homologous
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Immunohistochemical study of the cells infiltrating human renal allografts by the ABC and the IGSS method using monoclonal antibodies.
|
| pubmed:publicationType |
Journal Article
|