|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1986-12-18
|
|
pubmed:abstractText |
BAYK8944, a calcium 'agonist' caused a slow depolarization of a proportion of CA1 hippocampal pyramidal cells and increased their input resistance. In voltage-clamped CA1 neurones BAYK8644 caused a decrease in depolarization-activated outward current. Reduction of depolarization-activated outward current was also produced by the Ca ionophore A23187. It is proposed that BAYK8644 and A23187 may cause suppression of outward current secondary to a prolonged increase in cytosolic Ca activity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0304-3940
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
8
|
|
pubmed:volume |
70
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
239-44
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2430239-3-Pyridinecarboxylic acid...,
pubmed-meshheading:2430239-Action Potentials,
pubmed-meshheading:2430239-Animals,
pubmed-meshheading:2430239-Calcimycin,
pubmed-meshheading:2430239-Calcium,
pubmed-meshheading:2430239-Guinea Pigs,
pubmed-meshheading:2430239-Hippocampus,
pubmed-meshheading:2430239-Ion Channels,
pubmed-meshheading:2430239-Membrane Potentials,
pubmed-meshheading:2430239-Neurons,
pubmed-meshheading:2430239-Nimodipine,
pubmed-meshheading:2430239-Potassium
|
|
pubmed:year |
1986
|
|
pubmed:articleTitle |
Excitatory action of BAYK8644 on hippocampal pyramidal neurones of the guinea pig in vitro.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
