Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1986-12-17
pubmed:abstractText
Mechanical responses elicited by rat interferon (IFN) were investigated in rat vascular smooth muscle cells (RVSMC) in primary culture. IFN induced a dose-dependent reduction in the apparent cell surface area, which was quantitatively comparable to, or even greater than, the response elicited by the alpha-adrenergic agent, phenylephrine. Neither mock-IFN nor rat IFN-neutralized with specific antibodies elicited such a response. The sensitivity of RVSMC to the mechanical effect of IFN was species specific. In addition, the effect of IFN was inhibited by the Ca2+ entry blocker, verapamil.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0197-8357
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
397-404
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Mechanical responses of rat vascular smooth muscle cells to rat interferon.
pubmed:publicationType
Journal Article, Comparative Study