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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1986-10-23
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pubmed:abstractText |
Using double immunogold staining procedures, calcitonin gene-related peptide (CGRP)-like and substance P (SP)-like immunoreactivities were localized at the ultrastructural level to guinea pig trigeminal ganglia, dorsal root ganglia and peripheral nerve fibres associated with the vascular system. CGRP-like and SP-like immunoreactivities were found consistently in large granular secretory vesicles (70-100 nm in diameter), and both peptide immunoreactivities were co-localized to the same vesicle in both sensory ganglion cells and within axons and their terminals in the adventitia and adventitial-medial border of the superior mesenteric artery. These results suggest that CGRP and SP are co-stored and may be released together from peripheral axons in the guinea pig.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0300-4864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
535-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2427663-Animals,
pubmed-meshheading:2427663-Calcitonin Gene-Related Peptide,
pubmed-meshheading:2427663-Cytoplasmic Granules,
pubmed-meshheading:2427663-Gold,
pubmed-meshheading:2427663-Guinea Pigs,
pubmed-meshheading:2427663-Histocytochemistry,
pubmed-meshheading:2427663-Immunosorbent Techniques,
pubmed-meshheading:2427663-Microscopy, Electron,
pubmed-meshheading:2427663-Nerve Tissue Proteins,
pubmed-meshheading:2427663-Peripheral Nerves,
pubmed-meshheading:2427663-Substance P
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pubmed:year |
1986
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pubmed:articleTitle |
Ultrastructural evidence for the coexistence of calcitonin gene-related peptide and substance P in secretory vesicles of peripheral nerves in the guinea pig.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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