Linked Life Data

2426236

Source:http://linkedlifedata.com/resource/pubmed/id/2426236

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1986-9-25
pubmed:abstractText
The ionic channels of hair cells play important roles in mechanoelectrical transduction, frequency tuning, and synaptic transmission. In the hair cells of the bullfrog's sacculus, transduction is mediated by mechanically gated, poorly selective channels located in the hair bundle. Statistical analysis of the variance in the transduction current measured under voltage-clamp conditions indicates that a cell has only a few hundred transduction channels, each with a conductance of approximately 17 pS at room temperature. The same cells employ a resonance in their membrane potential to enhance their frequency selectivity in responses to mechanical stimuli. Voltage-clamp studies indicate that the resonance results principally from the interplay of two ionic conductances, a voltage-sensitive Ca2+ conductance and a Ca2+-sensitive K+ conductance.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-5955
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-7
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
The ionic channels of a vertebrate hair cell.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't