Linked Life Data

2425502

Source:http://linkedlifedata.com/resource/pubmed/id/2425502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1986-8-21
pubmed:abstractText
We compared antibody levels to Bacteroides fragilis in patients with different stages of Crohn's disease and ulcerative colitis to normal controls using an ELISA. IgM-titers were low in patients with Crohn's disease who had undergone surgery of small or large bowel but normal in all other groups of patients. Similarly, IgG-titers were similar to control values in all patients with uncomplicated Crohn's disease but elevated in patients with complicating fistula, colonic Crohn's disease and resected small or large bowel. IgM- and IgG-titers were elevated in patients with ulcerative colitis. However, only sera from patients with fistula inhibited increased the binding of a monoclonal antibody specific for B. fragilis thus demonstrating their specificity for B. fragilis. This findings could point to an involvement of B. fragilis in the formation of fistula in patients with Crohn's disease.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0044-2771
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-75
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
[Antibody titer to Bacteroides fragilis is increased in Crohn disease patients with fistula development].
pubmed:publicationType
Journal Article, English Abstract