Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-8-14
pubmed:abstractText
The natural killer cell cytotoxicity was studied in the 4 hour and 18 hour cytotoxic reaction with cultured human tumour cells (K562 and lung adenocarcinoma) labelled by 51Cr. The natural killer cell activity of cancer patients was lowered only in 4 hour cytotoxic reaction with target cells K562. The natural and recombinant leucocyte interferon and natural immune interferon stimulated in vitro the activity of natural killer cells in most of the experiments (80.5 %) in the 4 hour and 18 hour cytotoxic reactions both from patients with initially lowered level, and with normal or high level of cytotoxic action of natural killer cells. In some experiments interferon preparations did not significantly influence the lysis of tumour cells or even suppressed the activity of effector cells. The heterogeneity of the population of natural killer cells and different immunomodulating effects of interferon were discussed.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0204-3564
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
44-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
[Effect of different types of interferon on the natural cellular cytotoxicity of lung cancer patients].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract