Linked Life Data

2424565

Source:http://linkedlifedata.com/resource/pubmed/id/2424565

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-8-4
pubmed:abstractText
Monoclonal antibody mabQ113 recognizes a polypeptide antigen which, in rat cerebellum, is confined exclusively to a subset of Purkinje cells which are organized into parasagittal bands. In this report we have explored the distribution of mabQ113 immunoreactivity in some other regions of the rat brain. The most interesting result was a dramatic differential staining of the habenular complex in which mabQ113 densely and uniformly stained the lateral habenula but did not stain the medial habenula. Within the lateral habenula reaction product is localized primarily in the cellular processes of astrocytes but there is also staining of neighboring neuronal dendritic and axonal profiles. The afferent and efferent tracts of the habenular nuclei are not immunoreactive and there was no systematic difference in staining between the afferent and efferent nuclear groups of the two habenular nuclei. The pattern of mabQ113 immunoreactivity in rat brain is distinct from previously described biochemical differentiation markers of the two nuclei and thus may serve as a useful probe to study habenular anatomy, development and function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
4
pubmed:volume
375
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-12
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
A survey of MabQ113 immunoreactivity in the adult rat brain: differential staining of the lateral and medial habenular nuclei.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't