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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-7-9
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pubmed:abstractText |
In blood smears from 527 females and 457 males examined for the presence of Y chromosomes in interphase nuclei, 0.6% false-positive results and 11% false-negative results were found. There was a clear tendency for the false-negative results to occur among those with small fluorescent or non-existing bands on the Y chromosome. The three false-positive females all had fluorescent chromosomal variants. In a comparison between female samples with and without chromosomal variants respectively, the former showed significantly higher false Y-body counts. There was a decrease in the number of Y-bodies with increasing age. There were no significant differences between staining with 0.1% Quinacrine mustard and 0.1% and 1% Mepacrine. This study provides a more solid basis for the use of Y chromosome detection in forensic medicine, for screening purposes etc.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0340-6717
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2423431-Adolescent,
pubmed-meshheading:2423431-Adult,
pubmed-meshheading:2423431-Age Factors,
pubmed-meshheading:2423431-Aged,
pubmed-meshheading:2423431-Child,
pubmed-meshheading:2423431-Child, Preschool,
pubmed-meshheading:2423431-False Negative Reactions,
pubmed-meshheading:2423431-False Positive Reactions,
pubmed-meshheading:2423431-Female,
pubmed-meshheading:2423431-Humans,
pubmed-meshheading:2423431-Infant,
pubmed-meshheading:2423431-Infant, Newborn,
pubmed-meshheading:2423431-Interphase,
pubmed-meshheading:2423431-Karyotyping,
pubmed-meshheading:2423431-Male,
pubmed-meshheading:2423431-Middle Aged,
pubmed-meshheading:2423431-Quinacrine,
pubmed-meshheading:2423431-Quinacrine Mustard,
pubmed-meshheading:2423431-Staining and Labeling,
pubmed-meshheading:2423431-Y Chromosome
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pubmed:year |
1986
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pubmed:articleTitle |
The frequency of false-positive and false-negative results in the detection of Y-chromosomes in interphase nuclei.
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pubmed:publicationType |
Journal Article,
Comparative Study
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