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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1986-6-10
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pubmed:abstractText |
Using monoclonal antibodies the immunogenic and allergenic characteristics of rye Group I were redefined by SDS-PAGE analysis and immunoblotting. The purified rye Group I from NIH possesses a major component of approximately 34000 Da against which most of the sera from grass-sensitive patients and none from non-atopic volunteers contain specific IgE antibodies. Monoclonal antibodies to rye Group I were raised and used to purify the antigen and to verify the cross-reactivity between grass extracts. The 3 monoclonal antibodies studied recognized different components of timothy grass and 2 of them recognized kentucky june grass but none recognized components of ragweed extracts.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-1759
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
53-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2422284-Allergens,
pubmed-meshheading:2422284-Antibodies, Monoclonal,
pubmed-meshheading:2422284-Cereals,
pubmed-meshheading:2422284-Cross Reactions,
pubmed-meshheading:2422284-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:2422284-Epitopes,
pubmed-meshheading:2422284-Immunoglobulin E,
pubmed-meshheading:2422284-Immunoglobulin G,
pubmed-meshheading:2422284-Immunosorbent Techniques,
pubmed-meshheading:2422284-Molecular Weight,
pubmed-meshheading:2422284-Poaceae,
pubmed-meshheading:2422284-Pollen,
pubmed-meshheading:2422284-Secale cereale
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pubmed:year |
1986
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pubmed:articleTitle |
Allergenicity and cross-reactivity of rye grass pollen extracts revealed by monoclonal antibodies.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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