Linked Life Data

2422238

Source:http://linkedlifedata.com/resource/pubmed/id/2422238

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1986-5-27
pubmed:abstractText
Cheek pouches were removed from anesthetized hamsters and were either tape-stripped or left intact and then mounted in Ussing chambers, where they were bathed in Krebs-Ringer bicarbonate saline. A potential difference could be measured across all pouches and was stable for over an hour across the unstripped pouches. The electrical resistance across the unstripped pouches was high (8960 omega.cm2), whereas the resistance across the tape-stripped pouches was significantly lower (p less than 0.01), suggesting that these pouches are likely to be more permeable than the unstripped pouches. Reflection coefficients of urea, ethanol, and glycerol were derived by means of streaming potentials. Values for intact pouches were all close to 1 and for tape-stripped pouches were 0.938, 0.822, and 0.509, respectively. Permeability coefficients for urea and ethanol across intact and tape-stripped pouches were, respectively, 12.5 X 10(-9)cm/min; 27.6 X 10(-9) cm/min; 2325 X 10(-9)cm/min; and 28471 X 10(-9) cm/min. The hamster cheek pouch has a high electrical resistance; it is an impermeable structure in which the keratin layer appears to provide a major barrier to the passage of water, ions, and certain solutes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-0345
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
673-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
A comparison of some of the permeability characteristics of intact and tape-stripped hamster cheek pouches in vitro.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't