Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1986-4-7
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pubmed:abstractText |
A 59-year-old white man had generalized lymphadenopathy, fever, weight loss, and hypercalcemia. Histologic examination of seven lymph nodes from three different anatomic sites revealed a diffuse histiocytic infiltrate containing numerous typical Michaelis-Gutmann (MG) bodies. Histochemical and immunohistochemical results confirmed the histiocytic nature of the predominant cell within the infiltrate. Approximately equal numbers of residual normal B-cells, T-helper, and T-suppressor cells were present. Electron microscopy revealed extracellular and intracellular MG bodies, many of which were membrane-bound. Special stains, electron microscopy, and lymph node culture did not demonstrate microorganisms. The histologic features of the infiltrate were those of malacoplakia. However, the disease behaved like a lymphoma, with the occurrence of lymphadenopathy and a fatal outcome.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0008-543X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
57
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1337-40
|
pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2418936-B-Lymphocytes,
pubmed-meshheading:2418936-Diagnosis, Differential,
pubmed-meshheading:2418936-Frozen Sections,
pubmed-meshheading:2418936-Histiocytes,
pubmed-meshheading:2418936-Humans,
pubmed-meshheading:2418936-Lymph Nodes,
pubmed-meshheading:2418936-Lymphatic Diseases,
pubmed-meshheading:2418936-Lymphoma,
pubmed-meshheading:2418936-Malacoplakia,
pubmed-meshheading:2418936-Male,
pubmed-meshheading:2418936-Middle Aged,
pubmed-meshheading:2418936-Staining and Labeling,
pubmed-meshheading:2418936-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:2418936-T-Lymphocytes, Regulatory
|
pubmed:year |
1986
|
pubmed:articleTitle |
Lymphadenopathy due to fatal histiocytic proliferative disorder containing Michaelis-Gutmann bodies.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|