Linked Life Data

2417815

Source:http://linkedlifedata.com/resource/pubmed/id/2417815

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-3-7
pubmed:abstractText
Lesion evidence indicates that the human medial temporal lobe (MTL) makes an important contribution to Recent Memory formation and retrieval very soon after a stimulus item is encountered. For verbal materials, this contribution is lateralized to the language dominant hemisphere. Evoked potentials recorded from the MTL during verbal recognition memory display two late endogenous components. Both show differences between repeated target words and non-repeated distractor words. The first component is usually negative and has an average latency of 460 msec. It is also observed in lexical decision and picture naming tasks. This component is similar in latency, morphology, and task correlates to the scalp-recorded N4 potential. This 'MTL-N4' is smaller in amplitude to words recognized as repeats and is largest in amplitude in the left MTL. The second component is usually positive and has an average latency of 620 msec. It is similar in morphology and MTL topography to the P3-like component evoked at 360 msec to rare tones in auditory discrimination tasks. This 'MTL-P3' is larger in amplitude to words recognized as repeats. Both components are of very large amplitude and invert polarity over short distances within the MTL. Hence, they appear to be locally generated in the MTL. The extent to which volume conduction of these MTL potentials contribute to scalp-recorded EPs is unclear. The MTL-N4 might be involved with memory formation and retrieval processes, and the MTL-P3 might index completion of the detection-recognition cycle.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0013-4694
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-59
pubmed:dateRevised
2008-9-9
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Human medial temporal lobe potentials evoked in memory and language tasks.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.