Linked Life Data

2417265

Source:http://linkedlifedata.com/resource/pubmed/id/2417265

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1986-2-7
pubmed:abstractText
In 1980 Oehme and co-workers [11] reported that Substance P (SP) has a dual effect on nociception, which is related to the pain threshold before SP administration. Our recent results showed that the N-terminal part of the SP sequence may be important to the hyperalgesic action, and the C-terminal part to the analgesic action of this peptide. The hyperalgesic effect of SP (and N-terminal fragments of SP) seems to be related to the "anti-stress" effect which was first demonstrated by Hecht and co-workers [5] and Oehme and co-workers [12]. Interaction of SP with opioid peptides could be the common reason of both the "anti-stress" effect and the hyperalgesic activity of SP.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
568-70
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Influence of substance P on nociception and stress.
pubmed:publicationType
Journal Article