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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-2-14
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pubmed:abstractText |
Twenty-two patients with cirrhosis and minute hepatocellular carcinoma less than 3 cm in diameter were followed for periods of 6-37 mo without specific treatment. The survival curve drawn by the Kaplan-Meier method showed a 1-yr survival of 90.7%, a 2-yr survival of 55.0%, and a 3-yr survival of 12.8%. The ultrasonic patterns of these masses in the liver were correlated with the size and showed a tendency to change from a low echo pattern to a low periphery and, finally, to a massive pattern. The growth speed calculated from the doubling time for tumor volume varied considerably from case to case with an average of 6.5 +/- 5.7 mo; it also changed in some cases during the observation period. Serum alpha-fetoprotein levels were generally low, rarely assisted in diagnosis, but tended to increase when the mass attained a diameter of greater than 3 cm; sudden acceleration in the rate of increase in alpha-fetoprotein level often coincided with a change of ultrasonic pattern to the massive one.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0016-5085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
289-98
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2416627-Aged,
pubmed-meshheading:2416627-Carcinoma, Hepatocellular,
pubmed-meshheading:2416627-Female,
pubmed-meshheading:2416627-Follow-Up Studies,
pubmed-meshheading:2416627-Humans,
pubmed-meshheading:2416627-Liver,
pubmed-meshheading:2416627-Liver Cirrhosis,
pubmed-meshheading:2416627-Liver Neoplasms,
pubmed-meshheading:2416627-Male,
pubmed-meshheading:2416627-Middle Aged,
pubmed-meshheading:2416627-Prognosis,
pubmed-meshheading:2416627-Time Factors,
pubmed-meshheading:2416627-Ultrasonography,
pubmed-meshheading:2416627-alpha-Fetoproteins
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pubmed:year |
1986
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pubmed:articleTitle |
Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis. A study in 22 patients.
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pubmed:publicationType |
Journal Article
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