Linked Life Data

2416301

Source:http://linkedlifedata.com/resource/pubmed/id/2416301

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1986-1-21
pubmed:abstractText
Separation of the alcoholic disease into a special nosological entity is founded on the basis of a clinico-morphological analysis. It is suggested to distinguish hepatic, gastric, pancreatic, cardiac, pulmonary and renal clinico-anatomical forms of the alcoholic disease that are most frequently observed in the therapeutic clinics. The most characteristic signs of the ethanol effect ("morphological markers") are as a rule observed in the exacerbation of the disease. They are as follows: alcoholic hyalin in hepatocytes and accumulation of intermediate filaments in the epithelial and mesenchymal cells. Pathology of the cytoskeleton is a morphological expression of the affected protein metabolism. Apart from the disturbance of the protein metabolism, the metabolism of lipids is damaged as well, this being manifested in the accumulation of fat inclusions in the cytoplasm of the different organ cells. Leucocytes and macrophages of the exudate in the alcoholic disease possess the signs of the functional insufficiency thus confirming the state of the immunodeficiency in alcoholics.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0004-1955
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Clinical morphology of alcoholism].
pubmed:publicationType
Journal Article, English Abstract, Review