Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1985-12-18
|
| pubmed:abstractText |
Synaptic vesicles were purified from rat brain synaptosomes by osmotic lysis and chromatography on CPG-3000 controlled-pore glass beads. Large (approximately 100 nm) synaptic vesicles containing the peptide substance P (SP) were shown to be immunoprecipitated by a monoclonal antibody previously shown by W.D. Matthew, L. Tsavaler and L.F. Reichardt (J. Cell Biol., 91 (1981) 257-269) to selectively immunoprecipitate small (approximately 50 nm) synaptic vesicles from brain. Precipitation of SP-containing vesicles showed a saturable dependence on antibody concentration. These findings constitute direct, immunochemical evidence that large, peptidergic synaptic vesicles and small synaptic vesicles from brain have a surface antigen in common.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0304-3940
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
30
|
| pubmed:volume |
60
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
231-7
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading | |
| pubmed:year |
1985
|
| pubmed:articleTitle |
Evidence that large synaptic vesicles containing substance P and small synaptic vesicles have a surface antigen in common in rat.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|