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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1985-12-19
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pubmed:abstractText |
Long-term inhalation studies were carried out to evaluate the toxic pulmonary effects of diesel engine emissions. Cats were exposed for over 2 years to whole, diluted diesel exhaust at levels expected to produce frank toxic effects. During the first 61 weeks of exposure, the cats received exhaust having a particulate level of 6 mg m-3. This was followed by a doubling of the exposure level from weeks 62 to 124 resulting in particulate levels of 12 mg m-3. No definitive pattern of pulmonary function response was observed following 61 weeks; however, a classic pattern of restrictive lung disease was found at 124 weeks. The significantly reduced lung volumes and diffusing capacity were indicative of a pulmonary interstitial response which was later verified by histopathology.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0260-437X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2414357-Animals,
pubmed-meshheading:2414357-Cats,
pubmed-meshheading:2414357-Fuel Oils,
pubmed-meshheading:2414357-Lung,
pubmed-meshheading:2414357-Lung Volume Measurements,
pubmed-meshheading:2414357-Male,
pubmed-meshheading:2414357-Petroleum,
pubmed-meshheading:2414357-Time Factors,
pubmed-meshheading:2414357-Vehicle Emissions,
pubmed-meshheading:2414357-Vital Capacity
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pubmed:year |
1985
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pubmed:articleTitle |
Pulmonary function responses in cats following long-term exposure to diesel exhaust.
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pubmed:publicationType |
Journal Article
|