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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1985-12-20
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pubmed:abstractText |
The neuronal population of dorsal root ganglia in mouse consists of various classes of ganglion cells which may be divided in turn into subclasses by using several criteria. In class A cells, membrane-bound organelles are distributed ubiquitously throughout the large perikarya. Subclass A alpha (12%), which is characterized by large clumps of Nissl substance separated by narrow strands of neuroplasm, lacks detectable carbonic anhydrase activity. Subclass A beta (16%) displays small clusters of Nissl substance isolated by broad channels of neuroplasm and a moderate activity of carbonic anhydrase. Subclass A gamma (8%) shows the most intense carbonic anhydrase activity and a lack of uptake for [3H]L-glutamine. In class B cells (63%), the small perikarya display a zonal distribution of the organelles. Subclass B alpha contains parallel cisternae of rough endoplasmic reticulum and acid phosphatase isoenzymes present in long and curved Golgi saccules. Subclass B beta displays straight Golgi saccules rich in acid phosphatase isoenzymes and a high affinity uptake for glutamine. Subclass B gamma is characterized by the absence of acid phosphatase isoenzymes and by the presence of substance P-immunoreactivity. Class C cells (1%) have the smallest size and the highest affinity uptake for glutamine. Thus subtypes of primary sensory ganglion cells may be identified by the concomitant use of multiple criteria.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
346
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
310-26
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2413965-Acid Phosphatase,
pubmed-meshheading:2413965-Animals,
pubmed-meshheading:2413965-Carbonic Anhydrases,
pubmed-meshheading:2413965-Cell Count,
pubmed-meshheading:2413965-Female,
pubmed-meshheading:2413965-Ganglia, Spinal,
pubmed-meshheading:2413965-Glutamine,
pubmed-meshheading:2413965-Histocytochemistry,
pubmed-meshheading:2413965-Immunoenzyme Techniques,
pubmed-meshheading:2413965-Male,
pubmed-meshheading:2413965-Mice,
pubmed-meshheading:2413965-Mice, Inbred C57BL,
pubmed-meshheading:2413965-Microscopy, Electron,
pubmed-meshheading:2413965-Substance P
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pubmed:year |
1985
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pubmed:articleTitle |
Neuronal subpopulations in the dorsal root ganglion of the mouse as characterized by combination of ultrastructural and cytochemical features.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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