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rdf:type |
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lifeskim:mentions |
umls-concept:C0021420,
umls-concept:C0027882,
umls-concept:C0028631,
umls-concept:C0031164,
umls-concept:C0032821,
umls-concept:C0037473,
umls-concept:C0442805,
umls-concept:C0547047,
umls-concept:C0700301,
umls-concept:C1285354,
umls-concept:C1533685
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pubmed:issue |
4
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pubmed:dateCreated |
1985-11-25
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pubmed:abstractText |
In voltage clamp experiments the ionic permeability mechanism of the neuron soma evoked by the injection of cyclic nucleotides can be estimated only by studying the reversal potential. The value of this potential allows to conclude that permeability is mainly increased by opening potential independent sodium channels. A delay of ionic current evoked by cyclic nucleotides is tenfold less than the time of cAMP diffusion to the membrane. This leads to a hypothesis about the cyclic nucleotide dependent mechanical opening of sodium channels.
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pubmed:language |
rus
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0006-3029
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
632-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2413903-Action Potentials,
pubmed-meshheading:2413903-Animals,
pubmed-meshheading:2413903-Cell Membrane Permeability,
pubmed-meshheading:2413903-Cyclic AMP,
pubmed-meshheading:2413903-Cyclic GMP,
pubmed-meshheading:2413903-Ion Channels,
pubmed-meshheading:2413903-Iontophoresis,
pubmed-meshheading:2413903-Neurons,
pubmed-meshheading:2413903-Potassium,
pubmed-meshheading:2413903-Pressure,
pubmed-meshheading:2413903-Sodium
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pubmed:articleTitle |
[Intraneuronal information processing. An increase in sodium and decrease in potassium permeability after injection of cyclic nucleotide and mechanical stimulation of the neuron].
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pubmed:publicationType |
Journal Article,
In Vitro,
English Abstract
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