|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1985-11-12
|
|
pubmed:abstractText |
A considerable blastomogenic effect of metabolite serotonin 5-methoxytryptamine (5-MOT) subcutaneously administered for a long time to C57BL/6 mice was established. This effect was decreased noticeably if the further metabolism of 5-MOT into 5-methoxyindolyl-3-acetic acid (5-MIAA) was blocked by pyrazidol. These results explain the fact that the blastomogenic effect of 5-MOT is not direct but is caused by the transformation of 5-MOT into its final carcinogenic metabolite 5-MIAA.
|
|
pubmed:language |
rus
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0204-3564
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
26-9
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2412783-5-Methoxytryptamine,
pubmed-meshheading:2412783-Animals,
pubmed-meshheading:2412783-Carbazoles,
pubmed-meshheading:2412783-Hydroxyindoleacetic Acid,
pubmed-meshheading:2412783-Mice,
pubmed-meshheading:2412783-Mice, Inbred C57BL,
pubmed-meshheading:2412783-Monoamine Oxidase Inhibitors,
pubmed-meshheading:2412783-Neoplasms, Experimental,
pubmed-meshheading:2412783-Tryptamines
|
|
pubmed:year |
1985
|
|
pubmed:articleTitle |
[Carcinogenic action of 5-methoxytryptamine related to its transformation into 5-methoxyindolyl-3-acetic acid].
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
