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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1985-10-7
|
pubmed:abstractText |
Idiotype-specific polyclonal antisera were prepared against myelin-binding human IgM paraproteins with specificity for the myelin-associated glycoprotein (MAG). Eight anti-idiotypic sera (6 against one monoclonal IgM and 2 against another) were tested by gel precipitation, immunoradiometric and ELISA assays for binding to the myelin-binding IgM paraproteins from 12 patients with demyelinating peripheral neuropathy. Anti-idiotypic antibodies bound only to the MAG-specific IgM used for immunization; there was no evidence of idiotypic cross-reactivity between the different IgM paraproteins.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0022-510X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
69
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
161-70
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2411877-Autoantibodies,
pubmed-meshheading:2411877-Demyelinating Diseases,
pubmed-meshheading:2411877-Epitopes,
pubmed-meshheading:2411877-Humans,
pubmed-meshheading:2411877-Immunoglobulin Idiotypes,
pubmed-meshheading:2411877-Immunoglobulin M,
pubmed-meshheading:2411877-Myelin Sheath,
pubmed-meshheading:2411877-Paraproteinemias,
pubmed-meshheading:2411877-Peripheral Nervous System Diseases
|
pubmed:year |
1985
|
pubmed:articleTitle |
Human monoclonal IgM autoantibodies with restricted antigenic specificity for myelin express unrelated idiotypes.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|