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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
|
| pubmed:dateCreated |
1985-7-29
|
| pubmed:abstractText |
Heart fragments obtained from human right atrium contain 1.5 +/- 0.2 micrograms of histamine per gram of wet tissue. Human heart spontaneously synthesizes significant amounts of PGI2, PGF2 alpha, PGE2 and TxA2. The Ca2+ ionophore A 23187 (0.5-3 micrograms/ml) dose-dependently induces histamine release and prostanoid production. Histamine (0.5-1 micrograms/kg/min) infusion in 10 normal donors produced an increase in heart rate and a significant depression of the ST segment. Selective H1 receptor stimulation in patients undergoing cardiac catheterization resulted in a decrease of the mean aortic pressure and of coronary vascular resistance.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0020-5915
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
77
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
174-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2409015-Basophils,
pubmed-meshheading:2409015-Blood Pressure,
pubmed-meshheading:2409015-Calcimycin,
pubmed-meshheading:2409015-Coronary Circulation,
pubmed-meshheading:2409015-Heart,
pubmed-meshheading:2409015-Histamine,
pubmed-meshheading:2409015-Histamine Release,
pubmed-meshheading:2409015-Humans,
pubmed-meshheading:2409015-Mast Cells,
pubmed-meshheading:2409015-Myocardium,
pubmed-meshheading:2409015-Staphylococcal Protein A,
pubmed-meshheading:2409015-Vascular Resistance
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Histamine and human heart.
|
| pubmed:publicationType |
Journal Article
|