Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-3-20
pubmed:databankReference
pubmed:abstractText
Novel, approximately 90 bp intervening sequences (IVs) were discovered within the 23S rRNA genes of S. typhimurium and S. arizonae. These non-rRNA sequences are transcribed and then excised during rRNA maturation. The rRNA fragments that result from the excision of the extra sequences are not religated. This results in fragmented 23S rRNAs. The excision of one IVS was shown to be catalyzed in vivo and in vitro by ribonuclease III. These IVSs are highly volatile evolutionarily, sometimes occurring in only some of the multiple rRNA operons of a particular cell. The sporadic nature of the occurrence of fragmented rRNAs among closely related organisms argues that such fragmentation is a derived state, not a primitive one. Possible sources of these IVSs, their parallels with internal transcribed spacers and introns in eukaryotes, and their possible roles in the evolutionary process are discussed.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0092-8674
pubmed:author
pubmed:issnType
Print
pubmed:day
9
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-14
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:2406020-Base Sequence, pubmed-meshheading:2406020-Blotting, Northern, pubmed-meshheading:2406020-Blotting, Southern, pubmed-meshheading:2406020-DNA, Ribosomal, pubmed-meshheading:2406020-Endoribonucleases, pubmed-meshheading:2406020-Escherichia coli, pubmed-meshheading:2406020-Escherichia coli Proteins, pubmed-meshheading:2406020-Genes, Bacterial, pubmed-meshheading:2406020-Molecular Sequence Data, pubmed-meshheading:2406020-Oligonucleotide Probes, pubmed-meshheading:2406020-Plasmids, pubmed-meshheading:2406020-RNA, Ribosomal, pubmed-meshheading:2406020-RNA, Ribosomal, 23S, pubmed-meshheading:2406020-Ribonuclease III, pubmed-meshheading:2406020-Salmonella, pubmed-meshheading:2406020-Salmonella arizonae, pubmed-meshheading:2406020-Salmonella typhimurium, pubmed-meshheading:2406020-Transcription, Genetic
pubmed:year
1990
pubmed:articleTitle
The excision of intervening sequences from Salmonella 23S ribosomal RNA.
pubmed:affiliation
Department of Biology, Indiana University, Bloomington 47405.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.