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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1990-3-28
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pubmed:abstractText |
Vasopressin may be involved in normal memory functions and may alleviate certain memory impairments. In this study, the usefulness of vasopressin to relieve electroconvulsive therapy (ECT)-induced memory impairment was evaluated using a placebo-controlled, random assignment, double-blind design. Patients were 33 depressives receiving bilateral ECT. Vasopressin, in a nasal spray, was administered q.i.d. from the first through the fifth ECT. Extensive memory testing evaluated both retrograde and anterograde amnesia; ratings of depression and patient ratings of subjective memory complaints were also obtained. Results did not show statistically significant evidence of benefit from vasopressin, though a number of comparisons were in the predicted direction. The role of vasopressin in reducing memory impairment of various types remains to be elucidated.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-3223
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
289-303
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:2405915-Administration, Intranasal,
pubmed-meshheading:2405915-Adult,
pubmed-meshheading:2405915-Aged,
pubmed-meshheading:2405915-Amnesia,
pubmed-meshheading:2405915-Depressive Disorder,
pubmed-meshheading:2405915-Electroconvulsive Therapy,
pubmed-meshheading:2405915-Humans,
pubmed-meshheading:2405915-Lypressin,
pubmed-meshheading:2405915-Memory,
pubmed-meshheading:2405915-Mental Recall,
pubmed-meshheading:2405915-Middle Aged,
pubmed-meshheading:2405915-Neuropsychological Tests,
pubmed-meshheading:2405915-Paired-Associate Learning,
pubmed-meshheading:2405915-Randomized Controlled Trials as Topic
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pubmed:year |
1990
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pubmed:articleTitle |
A placebo-controlled evaluation of vasopressin for ECT-induced memory impairment.
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pubmed:affiliation |
Psychopharmacology Research Association of Princeton, New Jersey 08540.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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