Linked Life Data

2405863

Source:http://linkedlifedata.com/resource/pubmed/id/2405863

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-3-13
pubmed:abstractText
We have proposed a set of changes in the design, analysis, and reporting of RA clinical trials which emphasizes the standardization of trials. We have suggested limiting the number of outcome measures used to those most sensitive to change and using uniform measurements of the same outcome measures in all clinical trials. We have also suggested that investigators focus on enumerating which patients improve in a trial, rather than on the mean level of improvement in treated patients versus the control patients. Finally, we have suggested the reporting of confidence intervals rather than simply stating P values. With the inauguration of these changes and more attention to other issues relevant to the quality of clinical trials, we hope that drug treatments of rheumatoid arthritis can be more easily compared with respect to effectiveness.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0004-3591
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
140-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Time for changes in the design, analysis, and reporting of rheumatoid arthritis clinical trials.
pubmed:affiliation
Arthritis Center, Boston University School of Medicine, Massachusetts 02118.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Review