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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-3-15
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pubmed:abstractText |
From December 1986 to April 1989, 38 patients with biliary atresia (eight newly diagnosed) were evaluated with doppler ultrasound of the portal venous system. Peak and mean velocities were computer derived from the spectral waveform. Good velocity was greater than 15 cm/s, intermediate velocity was 8 to 14 cm/s, abnormal velocity was less than 7 cm/s or hepatofugal. Patients were grouped according to clinical status: group 1 (n = 14), normal liver function; group 2 (n = 15), recurrent cholangitis; group 3 (n = 2), established bile drainage but complicated cirrhosis; group 4 (n = 7), failed portoenterostomy. All patients with normal liver function (group 1) had good or intermediate velocities. Thirteen of 15 patients with recurrent cholangitis (group 2) had good or intermediate velocities. Both patients in this group with abnormal velocities required transplantation. In group 3 the patient with abnormal velocity is on the transplant waiting list. In group 4, abnormal velocities preceded or coincided with deterioration of liver function in five of seven patients. Doppler ultrasound provides useful anatomic information, determines direction of flow, quantitates velocity of flow, and, when performed serially, provides adjunctive information on liver status in children with biliary atresia. These preliminary results suggest that patients with abnormal or significantly decreasing velocity are destined for transplantation. Patients with good portal venous velocity warrant ongoing, aggressive surgical management.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-3468
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
146-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2405146-Adolescent,
pubmed-meshheading:2405146-Biliary Atresia,
pubmed-meshheading:2405146-Blood Flow Velocity,
pubmed-meshheading:2405146-Child,
pubmed-meshheading:2405146-Child, Preschool,
pubmed-meshheading:2405146-Female,
pubmed-meshheading:2405146-Humans,
pubmed-meshheading:2405146-Infant,
pubmed-meshheading:2405146-Liver,
pubmed-meshheading:2405146-Liver Diseases,
pubmed-meshheading:2405146-Liver Transplantation,
pubmed-meshheading:2405146-Male,
pubmed-meshheading:2405146-Portal Vein,
pubmed-meshheading:2405146-Ultrasonography
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pubmed:year |
1990
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pubmed:articleTitle |
Portal venous velocity in biliary atresia.
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pubmed:affiliation |
Department of Surgery, University of Colorado School of Medicine, Denver.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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