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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1990-10-23
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pubmed:abstractText |
The ability of haloperidol (0.1 mg/kg) to reduce the amphetamine-induced (2 and 5 mg/kg) increase in ascorbic and uric acid in anterior caudate and in nucleus accumbens was tested using voltammetry in vivo. In both areas, haloperidol reduced the amphetamine-induced increase in uric acid. In both areas, haloperidol only marginally affected the amphetamine-induced increase in ascorbic acid. Amphetamine-induced increases in uric acid were more nearly dose-related than changes in ascorbic acid. Of the two compounds, uric acid seems more likely to be associated with dopamine.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0024-3205
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
735-42
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2402194-Amphetamine,
pubmed-meshheading:2402194-Analysis of Variance,
pubmed-meshheading:2402194-Animals,
pubmed-meshheading:2402194-Ascorbic Acid,
pubmed-meshheading:2402194-Caudate Nucleus,
pubmed-meshheading:2402194-Electrophysiology,
pubmed-meshheading:2402194-Haloperidol,
pubmed-meshheading:2402194-Male,
pubmed-meshheading:2402194-Nucleus Accumbens,
pubmed-meshheading:2402194-Rats,
pubmed-meshheading:2402194-Rats, Inbred Strains,
pubmed-meshheading:2402194-Septal Nuclei,
pubmed-meshheading:2402194-Uric Acid
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pubmed:year |
1990
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pubmed:articleTitle |
The effects of haloperidol and amphetamine on ascorbic acid and uric acid in caudate and nucleus accumbens of rats as measured by voltammetry in vivo.
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pubmed:affiliation |
Dept. of Psychology, Texas Christian University, Fort Worth 76129.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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