| pubmed-article:2401682 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0006434 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0022801 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0012472 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:2401682 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:2401682 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2401682 | pubmed:dateCreated | 1990-10-24 | lld:pubmed |
| pubmed-article:2401682 | pubmed:abstractText | Prostaglandin E2 (PGE2) is a very important immunosuppressive substance that is synthesized and released by all macrophages including Kupffer cells (KCs). In this study the changes of PGE2 released by KCs were evaluated in a burned guinea pig model. Prostaglandin E2 was released by KCs from burned guinea pigs at a consistently and significantly high level when stimulated with endotoxin. On postburn day 8, KCs that were cocultured with hepatocytes released significantly less PGE2. There was also a significant decrease in antibody-dependent cell-mediated cytotoxicity on postburn day 1. Kupffer cells can mediate immune suppression in burn injury by a prolonged increased production of PGE2 that has immunosuppressive effects on other cells and by a decreased cytotoxic effect soon after burn injury. | lld:pubmed |
| pubmed-article:2401682 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2401682 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2401682 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2401682 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2401682 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2401682 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2401682 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2401682 | pubmed:issn | 0273-8481 | lld:pubmed |
| pubmed-article:2401682 | pubmed:author | pubmed-author:WoodSS | lld:pubmed |
| pubmed-article:2401682 | pubmed:author | pubmed-author:EneFF | lld:pubmed |
| pubmed-article:2401682 | pubmed:author | pubmed-author:OgleJ DJD | lld:pubmed |
| pubmed-article:2401682 | pubmed:author | pubmed-author:AlexanderJ... | lld:pubmed |
| pubmed-article:2401682 | pubmed:author | pubmed-author:OgleC KCK | lld:pubmed |
| pubmed-article:2401682 | pubmed:author | pubmed-author:WardenG DGD | lld:pubmed |
| pubmed-article:2401682 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2401682 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:2401682 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2401682 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2401682 | pubmed:pagination | 287-94 | lld:pubmed |
| pubmed-article:2401682 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:meshHeading | pubmed-meshheading:2401682-... | lld:pubmed |
| pubmed-article:2401682 | pubmed:articleTitle | The increased release of prostaglandin E2 by Kupffer cells from burned guinea pigs. | lld:pubmed |
| pubmed-article:2401682 | pubmed:affiliation | Shriners Burns Institute, Cincinnati, OH 45219. | lld:pubmed |
| pubmed-article:2401682 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2401682 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2401682 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
