Linked Life Data

2401095

Source:http://linkedlifedata.com/resource/pubmed/id/2401095

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-10-26
pubmed:abstractText
A study of 57 Asian Indian patients with Graves' disease revealed a significant increase in the frequency of HLA-DQW2 (61.4%) as compared to the control population (22.6%) giving a relative risk of 5.4. Less prominent but statistically significant increase in the frequency of HLA-A10 (29.8% patients as opposed to 10.5% controls) and HLA-B8 (28.1% patients as opposed to 8.7% controls) was also observed. Further, patients carrying the phenotypes HLA-A10 and HLA-B8 were more prone to develop the disease at a younger age. Two HLA haplotypes, namely A10-B8 and B8-DR3, were found in significant linkage disequilibrium in our patients with Graves' disease. Patients carrying these haplotypes also had a tendency to develop the disease at an earlier age.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0300-0664
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
HLA antigens in Asian Indian patients with Graves' disease.
pubmed:affiliation
Department of Endocrinology, All-India Institute of Medical Sciences, New Delhi.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't