Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1990-10-26
|
| pubmed:abstractText |
We diagnosed a 3-year-old boy as type C Niemann-Pick disease by studies on cultured fibroblasts; sphingomyelinase activity was almost normal, but esterification of exogenously administered cholesterol was deficient. Also sparse cultures of his fibroblasts developed a relatively intense fluorescence with filipin that was not observed either in normal or type B Niemann-Pick fibroblasts. We tried to treat him with dimethylsulfoxide (DMSO), 100 mg-120 mg/day for a year, but it had clinically insufficient effect on our case.
|
| pubmed:language |
jpn
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0029-0831
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
381-5
|
| pubmed:dateRevised |
2008-12-25
|
| pubmed:meshHeading |
pubmed-meshheading:2400614-Child, Preschool,
pubmed-meshheading:2400614-Cholesterol,
pubmed-meshheading:2400614-Dimethyl Sulfoxide,
pubmed-meshheading:2400614-Esterification,
pubmed-meshheading:2400614-Fibroblasts,
pubmed-meshheading:2400614-Humans,
pubmed-meshheading:2400614-Male,
pubmed-meshheading:2400614-Niemann-Pick Diseases,
pubmed-meshheading:2400614-Skin,
pubmed-meshheading:2400614-Sphingomyelin Phosphodiesterase,
pubmed-meshheading:2400614-Tomography, X-Ray Computed
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
[A case of type C Niemann-Pick disease].
|
| pubmed:affiliation |
Department of Pediatrics, Matsue Red Cross Hospital.
|
| pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|